Spoke to a guy working on bioHDF (GeoSpiza) over lunch. Missed his talk yesterday. Alternative to SAMtools BAM format. HDF has been around for a long while, they’ve stuck a Bio layer on top of it. Plan is to biolib-ify it to get Bio-perl |java|python|condutor) integration. Might be worth thinking about for the Gbrowse2 display of short read data?